Gw-501516 is often grouped with selective androgen receptor modulators (SARMS) but technically it is something known as a PPAR receptor agonist. The compound was originally developed in 1992 as a joint enterprise between pharmaceutical giants GlaxoSmithKline and Ligand, but the application to the FDA was dropped when a possible link to cancer was found.
Prior to this the scientists had discovered that Cardarine SARM binds to the PPAR receptor, which altered the gene activity responsible for the expenditure of energy. In other words, it activates the same pathways in the body which are in use when the body is exercising.
The initial concept was to identify a product for cardiovascular disease, and gw501516 cardarine certainly seemed to fit the bill.
As well as decreasing LDL, increasing HDL and protecting against diabetes, cardarine also boasts some incredible fat burning qualities too. Taking this drug changes the way the body metabolizes nutrients, promoting glucose uptake and reducing the amount of fat stored.
The compound is still available for legal purchase, but not for use as a supplement, or for consumption in any form.
Cardarine works well as part of either a steroid or SARMS cycle and is a great addition, complementing other actions and enhancing the results.
Because it is virtually free of all side effects, cardarine can be stacked with a great range of other drugs and supplements without causing unwanted interactions.
In fact, using gw1516 can even help to counteract some of the unwanted effects, particularly with trenbolone. Some of the side effects of trenbolone include lack of cardiovascular endurance and shortness of breath; cardarine can help to counteract this.
How it is administered
Gw 50156 results are obtained through administration of the compounds via an oral route, typically in liquid form. The consensus is that the most effective method is to squirt the dose directly into the mouth and then immediately follow with a mouthful of water or juice.
Taking a dose of around 10-15mgs per day on an eight week cycle will deliver improvements in endurance and stamina as well as fat loss.
However, for athletes looking to maximize the benefits, a gw 50516 dose of 20mg for up to 12 weeks is recommended.
Half life info
The half life of Cardarine is 20-24 hours which means that it only needs to be taken once per day. Some athletes prefer to use a divided dose method, taking half in the morning and the other half later in the day.
Use in sports
Because of its performance enhancing benefits, gw501516 has been highly sought after within sport, but in 2009 WADA added it specifically to its list of banned substances. Prior to this date it was still not permitted, but was considered to be part of the generic group of drugs which affect genes.
WADA now have a test which can check for gw1516 results, making the drug easier to track. Athletes who are subject to testing should be aware of the regulations relating to the use, and the potential penalties.
This is where gw1516 really excels because its fat burning qualities are almost unrivaled.
When under consideration by GSK, the drug was being assessed for use in the fight against obesity, because it shed fat even without a restricted diet. The really interesting part for bodybuilders is that cardarine achieved this without demonstrating any simultaneous catabolic effect, thus creating a performance enhancing drug which cuts beautifully without any muscle loss.
Although gw 50156 results are most often associated with fat loss, the drug can be a real asset to a bulking stack.
Because of its ability to cut fat while protecting muscle mass, gw1516 is a very beneficial to any bulking stack. The cardarine fat loss actions help to prevent bulk from being too soft or puffy, while simultaneously helping to preserve and promote muscle gains.
Strengthening and recomping
For those who are in the right shape to consider recomping, cardarine stacked with ostarine and andarine will provide excellent results.
If you’re looking to pile on huge quantities of muscle while recouping you might want to look at bulking and strengthening instead. Recomping isn’t the right approach for anyone who needs to add serious mass and no stack will be properly effective to achieve this.
Cardarine is a drug which is good for your health in lots of different ways. From purely a health perspective you can expect your cholesterol to be lower, your risk of developing diabetes to fall and better cardiovascular health.
For athletes, gw1516 provides far superior endurance, providing the capacity to train longer and harder, leading to quicker lean muscle gains. It is also an incredible fat burning compound, achieving this result without depleting the muscles.
Potential side effects
Compared to anabolic steroids and other performance enhancing drugs, SARMS side effects are minor. In extensive studies carried out, Cardarine side effects were shown to be virtually non-existent with no adverse reactions.
One study appeared to show that gw 50156 side effects included the growth of cancer cells but on further inspection, the results could be considered misleading. The study of gw1516 which was carried out on mice included 1000 times the recommended dose, taken over a prolonged period of time. As no individual would be taking such an inflated level of gw501516, there is debatable value attached to this particular study. Nevertheless, despite the criticism of this study, it was sufficient for GSK to drop the project so shouldn’t be dismissed completely.
In all other studies, Cardarine has not produced any discernible side effects.
Because Cardarine has never been approved or licensed for use in humans, no contraindications have ever been listed.
However, because of the link with cancer, it would be prudent for anyone with a strong family history of cancer, a history of cancer themselves or any kind of condition which involves the uncontrolled growth of tumors or cells to avoid taking cardarine.
Is it safe for women to use?
SARMS for women are much easier to find that anabolic steroids, because in many cases there’s not the same risk of virilization.
With gw501516 there is no androgenic action whatsoever, so that means that the usual virilization risks simply don’t exist.
Will PCT be required?
Cardarine causes no suppression of the natural production of testosterone so there is no need for PCT, regardless of how long the SARMS cycle is.
It’s easy to buy SARMS online but the difficulty with finding gw501516 for sale is that it is only sold for the purposes of research. Sourcing the product can therefore be more challenging but it’s essential to make sure the purchase is made from a trustworthy source to ensure the proper strength liquid is being provided.
As a general guide from the companies who have SARMS for sale, expect to pay approximately 0 for a 30ml bottle at the strength of 20mg per ml.
Legality of purchase and its usage in the US
Gw 50156 for sale for use as a supplement can’t be found legally in the US as it’s never been passed as safe for human consumption due to GSK ceasing research.
However, as mentioned above, it is possible to buy gw501516 in the US, UK, and Europe because it’s available to purchase for the purposes of research.
As it’s never been made available for human consumption, and is not recognized as a legitimate drug gw1516 does not currently have any penalties affixed to the purchase or possession. This is in stark contrast to the penalties for using, distributing and even possessing anabolic steroids, another reason why some bodybuilders are opting for this compound instead.
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